Avoiding Cancers

According to vast amounts of information available on the Internet, Cancer cells are acidic while healthy cells are alkaline. When the body’s pH becomes acidic, oxygen levels decline proportionately and begin to choke out the cells ability to make energy and eliminate wastes. Acidic pH creates a hostile internal environment which makes the body struggle to get its nutrient needs met. The more acidic you become the worse you will most likely feel. This is a main factor in feeling tired and worn out. Even though you are breathing oxygen, your cells can’t get it and you just can’t get the energy you want out of your body.

It is widely believed that chronic diseases (like cancer) need an acidic environment to thrive. Every cancer researcher surely knows that cancer cannot survive in an alkaline environment? In fact, there is evidence to suggest that if a cancer tumor is put into a beaker with an alkaline media, the cancer will die within 3 hours. This is why eating with an alkaline pH in mind is so important. Most people are scared of getting cancer and now you know there is something positive you can do about it...keep your tissues alkaline!

What this information suggests is that, if you eat and drink the foods that will make your blood and body lean more towards the alkaline end of the pH scale (and don't overdo it, as imbalance in anything is not good!), theory has it that you can reverse the growth of cancerous cells to healthy cells and/or kill off the cancer cells altogether. I like that theory and think it’s worth the effort. If it IS true, do you really believe that Medical Science would want it to be Public?! Onward…

Broccoli
Effective against: most cancers
Works because: the slightly bitter flavor of broccoli (and its cousins Brussels sprouts, cabbage and cauliflower) is the reason for the impressive track record these vegetables have in deterring cancer. The bitter chemicals isothiocyanates and glucosinolates actually interfere with cancer progression and deactivate harmful oestrogens associated with hormonal cancers such as breast and ovarian cancers.

Garlic
Effective against: stomach, colon and most cancers
Works because: the smelly compounds in garlic are potent anti-cancer agents. All of the onion family, including leeks and shallots, contain these compounds but garlic is the most rich. Trials have shown that chemically induced cancers can be interrupted by the active compounds formed from allicin from garlic. To get the most out of garlic chop the clove and leave it to `mature' in the air for 15 minutes, and then use it in your cooking. Heating prior to this 'maturation time' by air neutralizes the important compounds.

Tofu
Effective against: breast, ovarian and prostate cancers
Works because: the isoflavones the Soya bean contains have a gently estrogen-mimicking effect in the human body. This helps to block the effects of more aggressive oestrogens, both natural and those from environmental chemicals from sources such as plastics and pesticides. This has the effect of limiting the risk of hormone-linked cancers in both women and men. Tofu may be more effective than other Soya products or Soya supplements as it has been fermented and so some potentially negative compounds are neutralized. The Japanese and Chinese who eat tofu regularly have low risks of these cancers.

Oily fish (Tuna, Salmon, Mackerel)
Effective against: colon, prostate and breast cancers
Works because: the omega-3 fatty acids have a profound effect on cell metabolism and communication. These fatty acids also act as anti-inflammatory agents, which may be a reason for their influence on colon cancer. When the diet is higher in polyunsaturated fatty acids, such as the omega-3s, it also limits the intake and the effects of saturated fats, which are linked to increased risk of some cancers.

Green tea
Effective against: most cancers
Works because: the active compound in green tea, EGCG (epigalocatechin-3-gallate) is believed to be one of the strongest antimutagenic compounds found in plants - this means it has the effect of stopping damage at a genetic level. It can also stop tumors forming their own blood supply network. Trials suggest that fairly high intakes are needed, around 10 cups a day, so replacing all hot drinks with green tea could have a beneficial effect, but only one cup a day might not. Green tea is much lower in caffeine than black tea or coffee and so is easier on sleep patterns as well.

Wholegrain cereals
Effective against: colon and breast cancers.
Works because: The fiber in whole grains, from cereals and whole meal bread, are important for gut and hormonal health. The fiber gives the colon something `to work with' and also promotes good bowel bacteria. Fiber is also important in eliminating excess oestrogens. Fiber-rich cereals include bran flakes, porridge oats and muesli, though it is best to choose low-salt and low-sugar versions.

Tomato puree
Effective against: prostate and breast cancers
Works because: the active compound in tomatoes is lycopene, one of the most potent free-radical scavengers, and seems to affect the activity of free-radicals created by tumors. Interestingly, the significant effects found against prostate and breast cancers are observed in cooked and processed tomato products, rather than raw tomatoes. This is because lycopene is made more absorbable by processing and so tomato juice, puree and canned tomatoes are most effective. It is even better to include a little olive oil when cooking with or consuming these because the oil increases absorption further.

Live yoghurt
Effective against: colon and breast cancers
Works because: the beneficial bacteria found in live yoghurt promotes gut health and improves the performance of the immune system. Regular yoghurt intake has been shown to increase levels of immune anti-cancer compounds such as interferon and natural killer cells. Because elimination of oestrogens happens in the colon, the health of the colon directly affects the development of breast cancer.

Oranges and carrots
Effective against: lung cancer particularly, and most cancers in general Works because: they are rich, respectively, in vitamin C and beta-carotene. All fruits and vegetables are rich in antioxidants and many are rich in these two compounds. These water-soluble antioxidants are important at protecting lung tissue, which is a very water-rich environment. High blood levels of these antioxidants are linked to much-reduced levels of lung, and other, cancers. However taking beta-carotene in supplement form may be ill-advised for smokers as trials have shown higher mortality levels, probably as smokers' lungs already have advanced damage. A diet high in fruits and vegetables is highly protective against lung cancer and even in countries where smoking is more prevalent, such as Greece and Spain, fruits and vegetables seem to be protective.

Linseeds (also called flax seeds)
Effective against: breast and colon cancers
Works because: the lignans they contain are gelatinous fibers which are highly protective against hormonal cancers. They convert in the bowel, in the presence of beneficial bacteria (see yoghurt above) to even more potent compounds which block the effects of estrogen. Additionally, like all fibers, they have a positive effect on bowel health - indeed one of the most effective remedies against constipation is to take one or two teaspoons of linseeds pre-soaked for 30 minutes in water or fruit juice. They are also particularly rich in omega-3 fatty acids.

Flaxseeds contain two cancer-preventive compounds: omega 3 fatty acids and lignans, which may reduce the risk of breast cancer and colon cancer. Ground flaxseeds, because they contain both the fiber and the oil, have more potent anticancer properties than flax oil alone. Cancer researchers suggest 25 grams of ground flaxseeds a day. You can grind your own in a coffee grinder or purchase pre-ground flaxseed meal, which mixes well in smoothies or sprinkled like bran flakes over yogurt and cereal.

Cruciferous Vegetables (Broccoli, Cabbage, Cauliflower and Brussels sprouts etc). Cancers are probably caused by saturated fatty diets which curtail the bodies fighting immunity. The best weapon against cancer is - HOLD YOUR BREATH - Cabbage, cauliflower, broccoli, radish, turnip and brussel sprouts - long classified as ANTI CANCER FOODS.

According to TrueHealth
The most powerful anti-cancer food of all is of course, a daily helping of seafood - for the complete range of the 72+ natural trace elements, without which we cannot help but sicken...or even, worse! The complete natural range of the 72 trace elements is the best anti-cancer food there is. This is the reason why the breast cancer rate is 21 times lower, the lung cancer rate is 36 times lower, the prostate cancer rate is 137 times lower, and the colon cancer rate 187 times lower among the Sinhalese and most likely, the people of India as well. Unlike Sri Lanka, India does not have a public health care system, hence the lack of figures for India.

Since SELENIUM and BROCCOLI seem to be synonymous with Anti-Cancer ratings, I wanted to give

you a bit of information as to where you can find these in their wonderful natural sources:

Food	Micrograms (μg)	Percent DV*
Brazil nuts, dried, unblanched, 1 ounce	544	780
Tuna, light, canned in oil, drained, 3 ounces	63	95
Beef, cooked, 3½ ounces	35	50
Spaghetti w/ meat sauce, frozen entrée, 1 serving	34	50
Cod, cooked, 3 ounces	32	45
Turkey, light meat, roasted, 3½ ounces	32	45
Beef chuck roast, lean only, roasted, 3 ounces	23	35
Chicken Breast, meat only, roasted, 3½ ounces	20	30
Noodles, enriched, boiled, 1/2 cup	17	25
Macaroni, elbow, enriched, boiled, 1/2 cup	15	20
Egg, whole, 1 medium	14	20
Cottage cheese, low fat 2%, 1/2 cup	12	15
Oatmeal, instant, fortified, cooked, 1 cup	12	15
Rice, white, enriched, long grain, cooked, 1/2 cup	12	15
Rice, brown, long-grained, cooked, 1/2 cup	10	15
Bread, enriched, whole wheat, commercially prepared, 1 slice	10	15
Walnuts, black, dried, 1 ounce	5	8
Bread, enriched, white, commercially prepared, 1 slice	4	6
Cheddar cheese, 1 ounce	4	6

*DV = Daily Value. DVs are reference numbers developed by the Food and Drug Administration (FDA) to help consumers determine if a food contains a lot or a little of a specific nutrient. The DV for selenium is 70 micrograms (ug). Most food labels do not list a food's selenium content. The percent DV (%DV) listed on the table indicates the percentage of the DV provided in one serving. A food providing 5% of the DV or less is a low source while a food that provides 10-19% of the DV is a good source. A food that provides 20% or more of the DV is high in that nutrient. It is important to remember that foods that provide lower percentages of the DV also contribute to a healthful diet. For foods not listed in this table, please refer to the U.S. Department of Agriculture's Nutrient Database Web site: http://www.nal.usda.gov/fnic/cgi-bin/nut_search.pl.

ALKALIZING FOODS
VEGETABLES Garlic Asparagus Fermented Veggies Watercress Beets Broccoli Brussel sprouts Cabbage Carrot Cauliflower Celery Chard Chlorella Collard Greens Cucumber Eggplant Kale Kohlrabi Lettuce Mushrooms Mustard Greens Dulce Dandelions Edible Flowers Onions Parsnips (high glycemic) Peas Peppers Pumpkin Rutabaga Sea Veggies Spirulina Sprouts Squashes Alfalfa Barley Grass Wheat Grass Wild Greens Nightshade Veggies	FRUITS Apple Apricot Avocado Banana (high glycemic) Cantaloupe Cherries Currants Dates/Figs Grapes Grapefruit Lime Honeydew Melon Nectarine Orange Lemon Peach Pear Pineapple All Berries Tangerine Tomato Tropical Fruits Watermelon PROTEIN Eggs Whey Protein Powder Cottage Cheese Chicken Breast Yogurt Almonds Chestnuts Tofu (fermented) Flax Seeds Pumpkin Seeds Tempeh (fermented) Squash Seeds Sunflower Seeds Millet Sprouted Seeds Nuts	OTHER Apple Cider Vinegar Bee Pollen Lecithin Granules Probiotic Cultures Green Juices Veggies Juices Fresh Fruit Juice Organic Milk (unpasteurized) Mineral Water Alkaline Antioxidant Water Green Tea Herbal Tea Dandelion Tea Ginseng Tea Banchi Tea Kombucha SWEETENERS Stevia SPICES/SEASONINGS Cinnamon Curry Ginger Mustard Chili Pepper Sea Salt Miso Tamari All Herbs ORIENTAL VEGETABLES Maitake Daikon Dandelion Root Shitake Kombu Reishi Nori Umeboshi Wakame Sea Veggies

ACIDIFYING FOODS
FATS & OILS Avocado Oil Canola Oil Corn Oil Hemp Seed Oil Flax Oil Lard Olive Oil Safflower Oil Sesame Oil Sunflower Oil FRUITS Cranberries GRAINS Rice Cakes Wheat Cakes Amaranth Barley Buckwheat Corn Oats (rolled) Quinoi Rice (all) Rye Spelt Kamut Wheat Hemp Seed Flour DAIRY Cheese, Cow Cheese, Goat Cheese, Processed Cheese, Sheep Milk Butter	NUTS & BUTTERS Cashews Brazil Nuts Peanuts Peanut Butter Pecans Tahini Walnuts ANIMAL PROTEIN Beef Carp Clams Fish Lamb Lobster Mussels Oyster Pork Rabbit Salmon Shrimp Scallops Tuna Turkey Venison PASTA (WHITE) Noodles Macaroni Spaghetti OTHER Distilled Vinegar Wheat Germ Potatoes	DRUGS & CHEMICALS Chemicals Drugs, Medicinal Drugs, Psychedelic Pesticides Herbicides ALCOHOL Beer Spirits Hard Liquor Wine BEANS & LEGUMES Black Beans Chick Peas Green Peas Kidney Beans Lentils Lima Beans Pinto Beans Red Beans Soy Beans Soy Milk White Beans Rice Milk Almond Milk

We live in an era where the majority of Americans think that diseases strike us because of either misfortune, genetics, or unknown factors beyond our control. When serious disease “strikes,” we run to doctors and expect them to fix us with a pill. Most people have no idea that most diseases—including cancers, heart disease, strokes, and diabetes—are the result of nutritional folly. Because they do not know that adults lived much longer centuries ago, they accept the myth that we are living healthier and longer today.

If we were taught from childhood that the diseases we suffer in the modern world are the tragic consequence of our toxic food environment, we wouldn’t be in today’s disgraceful situation—where people graduate from high school, college, and even graduate school without learning how to protect, preserve, and restore their precious health. With proper health education, we would learn that our bodies are powerfully resistant to disease when nutritional needs are met. Instead, we have become the victims of the high-tech, mass-produced food culture that is fueling a cancer epidemic unrivaled in human history.

Chemotherapy Mentality
Our technologically-advanced society is suffering from the highest rates of cancer ever seen in human history, rates that are also much higher than in less developed parts of the world. Since 1999, cancer has surpassed heart disease and has become the leading cause of age adjusted mortality for Americans younger than 85. Despite more than a hundred billion dollars in cancer research— invested largely in the development of drug chemotherapy and screening and detection techniques—we have lost the war on cancer. While there has been a slight reduction of cancer-related deaths in the last 25 years, this is largely the result of the decrease in lung cancer deaths that has resulted from a reduction in cigarette smoking during this timeframe. Mortality rates for most cancers have stayed remarkably steady.

Chemotherapy has contributed to the progress made against cancer deaths from fast-growing cancers, such as leukemia, lymphoma, testicular cancer, and childhood cancers such as osteogenic sarcoma. But for the major cancers affecting most adult Americans, chemotherapy adds less than one year of disease-free life to those treated.

Science or Profits?
At present, pharmaceutical companies— not independent medical or scientific researchers—control the vast majority of research and clinical trials. We have lost the judgment and rationale of independent experts and now depend on drug companies to honestly report the risks and benefits of drugs they manufacture and sell. This is like asking the fast-food industry to be in charge of our nutritional advice. The medical studies that drug companies pay for and publicize are heavily biased in favor of the drugs they sell. The economically powerful pharmaceutical industry and the large chemical-food conglomerates wield undue influence on government and the media. Accurate nutritional information is rarely reported because the media cannot produce stories that go against the interests of their advertisers. Instead, the media is quick to report on drug company press releases—self-serving propaganda announcing new anticancer “breakthroughs” that reinforce the myth that we are winning the war against cancer.

Mythical Breakthroughs
Most often, the so-called “benefits” described by drug companies announce improved “response rates,” for example, when tumor burden is lessened. But an improved response rate means little if the patient does not survive longer. And even the cancer industry’s meager definition of survival—living 5 years beyond diagnosis—can be misleading. If “advances” in chemotherapy result in a higher percentage of people surviving for 5 years than did previously, that can be reported as “progress.” But if most of them still die between years 5 and 10, it hardly can be called a big success, especially if the same number or more people would have survived 10 years or longer without the chemotherapy.

Unless overall survival and quality of life are improved, it matters not if chemotherapy resulted in tumor shrinkage, or if a slight increase is seen in 5-year survival statistics. By using virtually meaningless terms like “response rates” and “disease-free survival,” researchers can report results that make chemotherapy look more effective than it really is.

Unless patients do some investigating of their own, they have no way of knowing that the glowingly optimistic results reported in the press—and too often parroted by their doctors—are designed to lead them to chemotherapy even though it is a poor choice for both quality and duration of life. The false perception that chemotherapy offers significant life-span benefits for cancer sufferers is dramatically juxtaposed by the fact that so many more people die of cancer today than they did years ago. In fact, a Swedish study showed that the risk of developing cancer and dying of it was three times higher in people born in the 1950s compared with those born in the 1880s. Since 1958, cancer has increased 55 percent in men and only slightly less in women.1

Does Chemotherapy Work?
Let’s see how effective chemotherapy actually is with a few common cancers.

A meta-analysis of chemotherapy for postmenopausal, estrogen receptor-positive women (the largest group of women with breast cancer) pooled the six largest studies to get the most accurate data on survival and complications. Here is what researchers concluded about the group treated with standard chemotherapy: “No significant survival benefit was observed.”2

In non-small cell lung cancer (the most common type), the 5- year survival is only about 10 percent. In stage 4, when the cancer has spread to distant sites, the 5-year survival is only 1.6 percent. After looking at multiple studies, it appears that treatment generally results in a very slight improved survival rate at 1 year, but this advantage disappeared at 30 months of follow- up.3

Even in small cell lung cancer where chemotherapy has proven effectiveness in life extension, the benefit adds only a few months of life, not years. And during this time the patient can experience serious—even life threatening— side effects from the treatment.

What Should You Do?
If you have cancer and are considering chemotherapy, it is wise to do a search on all of the studies done on the recommended therapy (using med-line, for instance), so an informed decision can be made. If this were done, most patients likely would refuse chemotherapy. Doctors generally hide and distort the realities of chemotherapy, talking to patients about “shrinking the cancer” and “killing cancer cells,” not mentioning the fact that the therapy has not been shown to extend life.

Every patient has to make her own decision. But if I were a woman with postmenopausal breast cancer, I would opt for surgery, without radiation and without chemotherapy, and would then pursue an aggressive nutritional protocol. I also would include antiestrogens if the tumor histology showed it to be estrogen receptor- positive.

War Against Good Nutrition
While the “war against cancer” is being fought with the wet noodle of chemotherapy, we are observing a significant increase in some cancers, such as malignant melanoma, multiple myeloma, and prostate cancer. Our population is heavier and as cancer-prone as ever. While we are pouring billions of dollars into drug companies and cancer centers, millions of people continue to die from what should be a preventable disease.

Almost nothing has been done to teach people about the power of nutritional excellence to protect against cancer. In fact, the media regularly reports that nutrition does not affect cancer. For example, a recent New York Times (G. Kolata, September 27,2005,“Science Times”) article reported that diet had only a “hypothetical” relationship with cancer. This ludicrous pronouncement was based on studies that showed that perimenopausal women who eat less fat still have high cancer rates. The Times evidently does not understand that modestly reducing fat and eating more chicken and pasta is not an anti-cancer program.

We are losing the war on cancer, and our government policies are actually worsening the problem. With all of the recent advances in science pointing to phytonutrient deficiency as the major cause of cancer, our efforts should focus on prevention; educating the public about proper diet and nutrition. Millions of lives can be saved. We also can eliminate the tragic consequences and family trauma of living with cancer—-diagnoses, surgeries, radiation, chemotherapies, suffering, and premature death, which come from the cancer and very often from the treatment.

Avoiding Cancer
Your body is a self-repairing and self-healing machine. Human cells have all the features necessary to protect themselves from chemical damage to their DNA that eventually results in carcinogenic changes. A cancer cell is essentially a normal cell whose DNA has been damaged to the point that it can no longer control its replication. The process that is creating our modern epidemic of cancer is twofold. One aspect involves the exposure of our cells to damaging stresses such as chemical carcinogens, radon, acrylamides, and high levels of saturated and trans fats and animal protein. At the same time, we have a woefully insufficient dietary intake of plant-derived nutrients, which renders our cells incapable of functioning to their fullest potential for repair and maintenance.

Our cells have built-in, powerful mechanisms to remove or destroy toxic substances, inhibit DNA damage, repair broken DNA cross-links, and remove cells that are injured or abnormal before they become cancerous. In recent years, the term phytochemicals has been used to refer to the thousands of newly-discovered nutrients supplied by plants that—-in addition to vitamins and minerals—-are necessary for maximal immune system protection and for the promotion of cellular detoxification and repair.

Most of our knowledge about what constitutes the optimal cancer prevention diet comes from both human population (epidemiological) studies and animal studies. Populations that have a high intake of natural, unrefined plant foods such as fruits, vegetables, seeds, nuts, and beans always have a low incidence of cancer, proportional to the intake of these phytochemcal-rich plant foods.

Even though other factors such as chemicals, pollution, and smoking play a role in cancer etiology, the scientific literature still illustrates that a better diet offers dramatic protection even against nondietary cancer promoters. For example, the Fiji Islands (where smoking rates are high) still has a dramatically lower incidence of lung cancer than Hawaii (where smoking rates are lower). This protection against lung cancer even in heavily smoking Fiji Islanders was shown to be the result of the high intake of green vegetables in Fiji.4

Examining data from numerous epidemiological studies, the World Cancer Research Fund concluded that the evidence that fruits and vegetables may reduce the risk of oral, esophageal, lung, stomach, colon, pancreatic, bladder, and breast cancer was convincing. No single substance in a plant-based diet accounts for this relationship; rather, it is the synergistic effect of multiple phytochemical compounds (which number in the thousands).

The National Cancer Institute recommends eating 5 servings of fruits and vegetables each day. However, scientific studies suggest that more is better and that much, much more is much, much better at reducing cancer risk. It is a national disgrace that very few Americans follow this very minimal recommendation to eat 5 servings of fruits and vegetables daily.

Cruciferous Vegetables
While fruits and vegetables are excellent sources of nutrients, the consumption of vegetables is more helpful in reducing cancer because they contain much higher amounts of cancer-protective compounds— especially green vegetables. Among these green vegetables, the cruciferous family has demonstrated the most dramatic protection against cancer. Cruciferous vegetables (broccoli, brussels sprouts, cauliflower, kale, bok choy, collards, arugala, watercress, and cabbage) contain a symphony of phytonutrients with potent anti-cancer effects. Isothiocyanates (ITCs), which are perhaps the best studied, have been shown to provide protection against environmental carcinogen exposure by inducing detoxification pathways, thereby neutralizing potential carcinogens.

These vegetables also contain indole-3- carbinol (I3C). Indole-3-carbinol has been shown to reduce the risk of breast cancer by decreasing estrogen activity. Important recent studies have shown that cruciferous vegetables and the compounds they contain can do the following:

prevent the replication of prostate cancer cells and induce death of cancerous cells;7

What makes these studies even more fascinating is the discovery of the gene/diet interaction, which has shown that high intake of greens and cruciferous vegetables provides the food factors necessary to interact with—and prevent— genetic defects from creating disease. This gene/diet interaction activates a battery of many genes, initiating DNA repair and other protection mechanisms.

These cellular repair and detoxification mechanisms are most powerfully induced by eating a mixture of both raw and cooked cruciferous plant foods. Some of the compounds are water soluble and heat stable, and absorption is increased when cooked, for example, in a soup. Other critical ITCs are heat sensitive and are better transmitted in the raw form.

Carotenoids & Polyphenols
Population studies show an association between high dietary intake of carotenoid-containing fruits and vegetables and reduced risk of prostate, breast, and head and neck cancers. A high dietary intake of fruits and vegetables provides a spectrum of carotenoids, including alphacarotene, gamma-carotene, betacryptoxanthin, zeaxanthin, lutein, and lycopene.

Vegetable juices (carrot, tomato, spinach, and other greens) represent a particularly potent form of carotenoids. Scientists have demonstrated that drinking carrot juice significantly reduces free radical damage to genes. Tomato juice and cooked tomatoes rich in lycopene and other potent antioxidants help reduce the oxidation of the “bad” LDL cholesterol and also have been shown to dramatically help protect against cancer. Carotenoid-rich extracts of carrots and tomatoes have been shown to substantially inhibit the early stages of liver cancer in animals.

Fruits also contain various key phytochemicals. For example, resveratrol, found in grapes, has been reported to exert a variety of anticancer effects. Studies have demonstrated that resveratrol causes growth inhibition of human colon and breast cancer cells. Ellagic acid, found in strawberries, grapes, blueberries, raspberries, and blackberries, is another polyphenol that has demonstrated anticarcinogenic potential in animal studies.

This article is from the Healthy Times newsletter, a complete archive of which is available to members of DrFuhrman.com.

References
1. Adami HO, Bergstrom R, Sparen P, Baron J. Increasing cancer risk in younger birth cohorts in Sweden, Lancet 1993 Mar 27;341(8848):773-777. 2. Hartman AR, Fleming GF, Dillon JJ. Metaanalysis of adjuvant cyclophosphamide/methotrexate/ 5-fluorouracil chemotherapy in postmenopausal women with estrogen receptor-positive, node-positive breast cancer. Clin Breast Cancer 2001;2(2):138-143. 3. Blackhall FH, Bhosle J, Thatcher N. Chemotherapy for advanced non-small cell lung cancer patients with performance status 2. Curr Opin Oncol 2005

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